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杭晓明

发布时间:2014-09-12 07:57:16

杭晓明

1972年出生。博士,教授,硕士生导师。

 

联系方式:

地址:大连海事大学环境系统生物学研究所206

邮编:116026

电话:0411-84723633-821

传真:0411-84725675

E-mail: hangxiaoming@dlmu.edu.cn

          hangxmdl@163.com

 

 

 

 

简历:

1992.09-1996.07           辽宁师范大学生物系 生物教育专业 学士学位

1996.09-1999.05           辽宁师范大学生物系 植物学专业 硕士学位

1999.05-2002.07           大连理工大学化工学院 生物化工专业 博士学位

2000.05-2002.07           清华大学,生命科学学院 完成博士学位论文的研究

2002.07-2005.07          Faculty of Life Sciences, University of Manchester, Postdoctoral associate researcher

2005.07 -2013.07                 大连海事大学环境系统生物学研究所 副教授

2006.07 -至今                     大连海事大学环境系统生物学研究所  硕士生导师

2011.03-至今                大连海事大学,生物系,系主任

2013.07-至今               大连海事大学环境系统生物学研究所 教授

 

国外访问进修经历:

2002.07 -2005.07   Faculty of Life Sciences, University of Manchester (UK)Postdoctoral associate researcher 参与完成1EU项目(Q5RS-2001-01465) “Calcium, the backbone of fish culture: importance in skeletal: formation, reproduction and normal physiology”

2004.02.15 – 03.15   Institute of Neuroscience, Radboud University Nijmegen (Holland),为期一个月的学术交流。

2005.03.04 – 03.14   Comparative and Molecular Endocrinology Group, CCMAR, Universidade do Algarve (Portugal),为期10天的学术交流。

 

研究领域:

以斑马鱼为模式生物材料,应用分子生物学、系统生物学和环境毒理学的方法,研究空间辐射和微重力,以及海洋污染引起的生物学效应及作用机制,为特殊环境的生物损伤评估和污染的预警预测提供帮助。

 

科研项目:

2013.01-2015.12国家自然科学基金青年科学基金项目“得克隆异构体在斑马鱼脑和肝脏中的生物应答及蛋白表达谱比较研究(41201521)”,项目负责人

2011.01-2013.12辽宁省科学技术厅自然科学基金计划项目“应用双荧光标记T-RFLP对大连新港石油泄漏污染区的生物损伤评价研究(201102012)”,项目负责人

2010.01-2011.12 航天医学基础与应用国家重点实验室开放基金项目“辐射和模拟微重力协同作用对斑马鱼抗氧化还原酶系的效应研究(SMFA09K07)”,项目负责人

2009.01-2010.11 国家海洋局海洋溢油鉴别与损害评估技术重点实验室2010年度开放基金项目“多环芳烃类污染物(萘)对斑马鱼损伤评价的生物标记物分析”,项目负责人

2010.01-2012.12国家科技支撑计划项目“渤海海岸带典型岸段与重要河口生态修复关键技术研究与示范(2010BAC68B02)”,项目第一参与人

2010.01-2011.12大连市甘井子区科技局项目“大连近岸海域重要污染物对水生生物的毒性评价研究”,第一参与人

2008.07-2010.07 辽宁省科技厅国际合作项目“近海岸外来有害生物快速检测技术与平台开发”,第一参与人

2007.09-2009.09 大连市甘井子区科技局项目“近海岸污染的分子生物学标记分析”,第一参与人

 

主要论著:

1. Biological Evaluation of Three Types of Inshore Pollution in Dalian City Using Ulva pertusa as Indicator. Hang Xiaoming, Wang Tao, Zhang Meng, Sun Yeqing. Advanced Materials Research. 2011, 356-360: 2278-2281. [EI]

2. Joint toxic effects of naphthalene and cadmium on zebrafish superoxide dismutase. Hang Xiaoming, Liu Cong, Liu Yang, Sun Yeqing. RSETE. 2011, V1: 435-437. [EI]

3. Effects of simulated-microgravity on development and p53 gene expression of zebrafish embryos. Hang Xiaoming, Li Hui, Ma Wenwen, Sun Yeqing. RSETE. 2011, V10: 8273-8276. [EI]

4. Acute and subacute toxicity of Bisphenol A on zebrafish (Danio rerio). Chen Xiaoning, Hang Xiaoming, Ke Weibo., Ma Zhanyuan, Sun Yeqing. Advanced Materials Research. 2011, 356-360: 138-141. [EI]

5. Identification of heavy-ion radiation-induced microRNAs in rice. Zhang Meng, Liang Shujian, Hang Xiaoming, Xiang Yingxia, Cheng Zhenlong., Li Wenjian., Shi Jinming, Huang Lei, Sun Yeqing. Advances in Space Research 47. 2011, 47 (6): 1054-1061. [SCI, 影响因子0.957]

6. Transcriptomic analyses of space-induced rice mutants with enhanced susceptibility to rice blast. Cheng Z. L, Liu M., Zhang M., Hang X. M., Lei C. L., Sun Y. Q. 2007, Advances in Space Research 40: 540–549. [SCI, 影响因子0.448]

7. Parathyroid hormone-related protein and calcium regulation in vitamin D-deficient sea bream (Sparus auratus). Abbink W, Hang X. M., Guerreiro PM, Spanings FA, Ross HA, Canario AV, Flik G. Journal of Endocrinology (2007) 193(3): 473-80. [SCI, 影响因子3.072]

8. Endothelin and calciotropic hormones share regulatory pathways in multidrug resistance protein 2 (Mrp2-) mediated transport. Wever K. E., Masereeuw R., Miller D. S., Hang X. M., Flik G. American Journal of Physiology-Renal Physiology (2007) 292 (1): F38-46.[SCI, 影响因子4.263]

9. PTHrP potentiating estradiol-induced vitellogenesis in sea bream (Sparus auratus, L.). Bevelander G. S., Hang X. M., Abbink W., Spanings T., Canario A. V., Flik G. General and Comparative Endocrinology  (2006) 149 (2): 159-65. [SCI, 影响因子2.290]

10. PTHrP regulation and calcium balance in sea bream (Sparus auratus L.) under calcium constraint. Abbink W., Bevelander G. S., Hang X. M., Lu W., Guerreiro P. M., Spanings T., Canario A. V., Flik G. Journal of experimental biology (2006) 209 (Pt 18): 3550-7 [SCI, 影响因子2.712]

11. Measurement of PTHrP, PTHR1 and CaSR Expression Levels in Tissues of Sea bream (Sparus aurata) Using Quantitative PCR. Hang X. M., Power D., Flik G., Balment R. J. Annals of New York Academy of Sciences (2005) 1040: 340-344.  [SCI, 影响因子1.971] 

12. Stanniocalcin in the Euryhaline Flounder (Platichthys flesus): Primary Structure, Tissue Distribution and Response to Altered Salinity. Hang X. M., Balment RJ. General and Comparative Endocrinology (2005) 144 (2): 188-195. [SCI, 影响因子2.290]

13. Production and characterisation of gilthead sea bream (Sparus auratus) recombinant parathyroid hormone related protein. Anjos L., Rotllant J., Guerreiro P. M., Hang X. M., Canario A. V. M., Balment R. J. & Power D. M., General and Comparative Endocrinology (2005) 143: 57-65. [SCI, 影响因子2.290]

14. Expression of seabream (Sparus aurata) parathyroid hormone-related protein (PTHrP) and functional study. Hang X. M., Balment R.J. Comparative Biochemistry and Physiology (2004) 137A (3/suppl.) p S141-143.

15. 大肠杆菌fadB缺失突变株的构建及对聚羟基脂肪酸酯积累的影响. 杭晓明,蔺兆星,王关林,陈国强. 大连理工大学学 (2003) 43: 595-598, 603 [EI, IF=0.305]

16. PCR Cloning of Polyhydroxyalkanoate Biosynthesis Genes from Burkholderia caryophylli and Their Functional Expression in Recombinant Escherichia coli. Hang X. M., Zhang G., Wang G. L.,Zhao X. H.,Chen G. Q. FEMS Microbiology Letters (2002) 210:49-54 [SCI, IF=2.057]

17. Polyhydroxyalkanoates Biosynthesis in Pseudomonas pseudoalcaligenus YS1. Hang X. M., Lin ZX, Chen JY, Wang GL, Hong K, Chen G. Q. FEMS Microbiology Letters (2002) 212:71-75 [SCI, IF=2.057]

18. PCR cloning of type II polyhydroxyalkanoate biosynthesis genes from two Pseudomonas strains. Zhang G, Hang X. M., Green P., Ho K. P., Chen G. Q. FEMS Microbiology Letters (2001) 198 (2): 165-170 [SCI, IF=2.057]

19. 细胞分裂素对辣椒子叶再生的影响. 李英慧,李艳,杭晓明,王朋.园艺学报 (2001) 28 (3): 270-272

20. 多分支心血管循环系统的建模和仿真研究. 冯宇军,杭晓明,田树军.中国生物医学工程学杂志(2000) 17:186-191 [EI, IF=0.247]

 

会议论文:

1. Cytoskeleton disorder and cell cycle arrest may be associated with the alteration of protein CEP135 by microgravity. Hang X. M., Wu D., Liu Z. Y., Li Y. X., Sun Y. Q. 40th COSPAR Scientific Assembly 2014, Life Sciences as Related to Space (F), Genetic, Epigenetic and Metabolic Changes of Biosystems in Spaceflight and Simulated Spaceflight Environment (F46).

2. Protein PSMD8 may mediate microgravity-induced cell cycle arrest. Hang X. M., Chen X. N., Xu D., Wu D., Sun Y. Q. 40th COSPAR Scientific Assembly 2014, Life Sciences as Related to Space (F), Genetic, Epigenetic and Metabolic Changes of Biosystems in Spaceflight and Simulated Spaceflight Environment (F46).

3. An integrated study on toxicity of Dechlorane Plus in zebrafish. Hang X. M., Jiang Y., Liu Y., Jia H. L., Sun Y. Q. 33rd International Symposium on Halogenated Persistent Organic Pollutants and POPs - DIOXIN 2013

4. Effects of simulated-microgravity on zebrafish embryonic development and microRNA expression. 39th COSPAR Scientific Assembly 2012, Life Sciences as Related to Space (F), Genetic, Epigenetic and Metabolic Changes of Biosystems in Spaceflight and Simulated Spaceflight Environment (F46).

5. Proteomic analysis of zebrafish embryos exposed to simulated microgravity. Hang X. M., Ma W. W., Wang W., Liu C., Sun Y. Q. 38th COSPAR Scientifc Assembly 2010, Life Sciences as Related to Space (F) , Genomic, Proteomic and Metabolic Changes of Biosystems in Spaceflight Environment (F46).

6. PHA synthases of pseudomonads: cloning and characterization. Zhang G., Hang X. M., Chen G. Q. 6th Intl Scientific Workshop on Biodegradable Polymers and Plastics & 9th Annual Meeting of BioEnvironmental Polymer Society, Hawaii (2000 December)

 

主讲课程:

本科:生物化学,生物化学实验,计划生育与优生常识(公选)

研究生:现代分子生物学实验技术,专业英语