教学与研究方向 主要从事微流控技术开发和生物标志物检测方面的教学和研究工作，承担本科生专业课《微流控生物分析技术基础》等课程的教学工作。研究方向为微流控系统开发和生物标志物微全分析，实现生物标志物实时现场检测，用于特殊环境（空间、远洋、野外等）下的生物医学研究、环境监测、健康检测等，为环境或健康风险评估提供基础数据和技术支撑。目前的研究重点是基于微流控芯片的核酸微全分析、免疫标志物多指标现场快速检测、模式生物（如线虫）自动化培养与监测等。已参与国家级科研项目近10项，发表学术论文和会议论文20余篇，参与编写微流控芯片专著2部，已授权专利近10项，目前申请专利近10项（含美国专利1项）。 教育及工作简历 ● 2015.12 –至今 大连海事大学，讲师，硕士生导师 ● 2012.04 – 2015.12中国科学院大连化学物理研究所，助理研究员 ● 2009.06 –2012.01 美国加州大学河滨分校，博士后 ● 2001.09 – 2009.01中国科学院大连化学物理研究所，理学博士 ● 1999.09 – 2001.07湖北回天胶业股份有限公司，研究助理 ● 1995.09 – 1999.07 武汉大学，理学学士 研究项目 作为负责人或骨干人员承担的科研项目包括： ● 航天医学实验项目（2018.12-2022.12） ● 载人航天空间应用系统重点领域科研项目子任务（2018.7-2022.12） ● 企业技术咨询项目（2017.4-2018.9） ● 海洋公益性行业科研专项子任务研究课题（2014.1-2017.12） ● 国家863计划项目子课题（2014/01-2016/12） ● 国家重大科学仪器设备开发专项子任务（2012.10-2017.9） 代表性论文 ● Runtao Zhong*, Shilin Liu, Guohao Zhang, Mengyu Wang, Yeqing Sun*. iso-μmGene: Isothermal amplification-based portable microfluidic system for simple, reliable and flexibly multiplexed Genetic identification and quantification. Analyst, 2020, in press. ● 钟润涛*，杨倩倩，刘琦，张普，刘清清，邱怡华，彭威，李沛然，王梦雨，王巍，孙野青*. 基于培养池阵列微流控芯片的单线虫并行分离条件考察，西北农业学报，2020，已录用. ● 苍小鑫，赵小明，钟润涛，王文霞，尹恒，朱靖博，丁燕*. 基于液滴微流控的壳寡糖植物免疫诱导剂荧光检测，农业工程学报，2017，33（2），302-307. ● Fan An, Yueyang Qu, Xianming Liu, Runtao Zhong*, Yong Luo*. Organ-on-a-chip: New Platform for Biological Analysis. Analytical Chemistry Insights, 2015, 10, 39-45. ● 余明芬，曾洪梅，钟润涛，赵小明，邱德文*. 基于微流控芯片电泳的番茄黄化曲叶病毒快速检测. 中国农业科学, 2014, 47(17), 3405-3413. ● Liangpin Xiao, Xianming Liu, Runtao Zhong, Kaiqing Zhang, Xiaodi Zhang, Xiaomian Zhou, Bingcheng Lin*, and Yuguang Du*. A rapid, straightforward and print house compatible mass fabrication method for integrating 3D paper-based microfluidics. Electrophoresis, 2013, 34 (20-21), 3003-3007. ● Runtao Zhong, Kenneth Flack and Wenwan Zhong*. Automatic Small RNA Extraction and Processing on a Multi-well/Multi-channel (M&M) Chip. Analyst, 2012, 137, 5546-5552. ● Runtao Zhong, Xiaoyan Pan, Lei Jiang, Zhongpeng Dai, Jianhua Qin, Bingcheng Lin*. Simply and reliably integrating micro heaters/sensors in a monolithic PCR-CE microfluidic genetic analysis system. Electrophoresis, 2009, 30(8), 1297-1305. ● Hua Xie, Bowei Li, Runtao Zhong, Jianhua Qin, Yisheng Zhu, Bingcheng Lin. Microfluidic device for integrated restriction digestion reaction and resulting DNA fragment analysis. Electrophoresis, 2008, 29(24), 4956-4963. ● Runtao Zhong, Dayu Liu, Linfen Yu, Nannan Ye, Zhongpeng Dai, Jianhua Qin, Bingcheng Lin*. Fabrication of two-weir structure-based packed columns for on-chip solid-phase extraction of DNA. Electrophoresis 2007, 28 (16), 2920–2926. ● Dayu Liu, Xiaomian Zhou, Runtao Zhong, Nannan Ye, Guohui Chang, Wei Xiong, Xiaodan Mei, Bingcheng Lin. Analysis of multiplex PCR fragments with PMMA microchip. Talanta, 2006, 68 (3), 616-622. ● Xiaomian Zhou, Shujuan Shao, Guandong Xu, Runtao Zhong, Dayu Liu, Jianwu Tang, Yanning Gao, Shujun Cheng, Bingcheng Lin. Highly sensitive determination of the methylated p16 gene in cancer patients by microchip electrophoresis. Journal of Chromatography B, 2005, 816, 145-151. ● Xiaomian Zhou, Dayu Liu, Runtao Zhong, Zhongpeng Dai, Dapeng Wu, Hui Wang, Yuguang Du, Zhinan Xia, Liping Zhang, Xiaodan Mei, Bingcheng Lin. Determination of SARS-coronavirus by a microfluidic chip system. Electrophoresis 2004, 25(17), 3032-3029. 会议论文 ● Runtao Zhong, Qianqian Yang, Qi Liu, Qingqing Liu, Yihua Qiu, Wei Peng, Yike Cai, Peiran Li, Shaohua Wang, Mengyu Wang, Wei Wang, Yeqing Sun*. Development of Nematode Microfluidic System for Space Radiation research. 7th International Systems Radiation Biology Workshop (7th ISRBW), Dalian, September 28-30, 2019 (Abstract, poster) ● Runtao Zhong, Liangsheng Hou, Yingbo Zhao, Mengyu Wang, Dan Xu, Yeqing Sun*. Microfluidic-based automatic immunofluorescent labeling of γ-H2AX in UV-irradiated CD4+ cells towards on-site rapid detection of radiation biomarkers. 7th International Systems Radiation Biology Workshop (7th ISRBW), Dalian, September 28-30, 2019 (Abstract, oral presentation) ● Runtao Zhong*, Liangsheng Hou, Dan Xu, Yeqing Sun*. Automatic immunofluorescent labeling of γ-H2AX in UV-irradiated CD4+ cells on a portable microfluidic device. 5th International Symposium on Space Radiation and Particle Radiotherapy (ISSRPRT2017), Suzhou, May 24-26, 2017 (Abstract, poster) ● Runtao Zhong, Xiaohui Wang, Bingcheng Lin*, Fengwu Bai, Naiyu Chi, Yuguang Du*. High-throughput screening for discovering glycosidase from metagenomic libraries using droplet-based microfluidics. 22nd International Symposium on Glycoconjugates (Glyco22), Dalian, June 23-28, 2013 (Abstract, oral presentation) ● Xiaohui Wang, Benwei Zhu, Fengwu Bai, Naiyu Chi, Runtao Zhong*, Yuguang Du*, Bingcheng Lin. Droplet-based microfluidics for high-throughput screening of glycosidases and rapid digestion of oligosaccharides. 5th International Symposium on Microchemistry and Microsystems (ISMM 2013), Xiamen, May 16-19, 2013 (Abstract, oral presentation) ● Runtao Zhong, Ni Li, Wenwan Zhong*. “Flexible microfluidic system for integrated purification and detection of small RNA from cell lysates”, PITTCON 2011, March 13-18, Atlanta, GA, USA (Abstract, poster) 所授课程 |
